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While the appetite suppressive effects of amylin and GLP-1 receptor agonists are known to involve direct actions in the brain 6,7,9,10,12,13,14 , uncovering the neuroanatomical site(s) of action and the physiological mechanisms that mediate the anorectic response remains an area of intense research focus

Insulin tends to cause fluid retention (edema), a type of swelling that occurs when the body is unable to remove extra fluids

But for others, its the opposite

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It binds to hair follicles, causing them to shrink and eventually stop producing hair